In microarray gene expression experiments, several diverse conditions in each experiment (e.g., time, doses, replicates) increase the data points from tens of thousands of measurements for a ...

For biologists, DNA microarrays present at once unprecedented opportunities and monumental challenges. In the opportunities column, microarrays produce genome-wide gene expression snapshots, ...

The impact of microarray technology on biology will depend on computational methods of data analysis. A supervised computer-learning method using support vector machines predicts gene function ...

Microarray Gene Expression Data Analysis: A Beginner's Guide by Helen Causton, John Quackenbush and Alvis Brazma is arguably the best of its kind in this regard. So who is the book aimed at?

The technology represents a unique approach to microarray analysis, enabling optimal signal-to-background ratio for biotin-labeled molecules, according to Margit Stadler, Ph.D., product line manager.

Microarray technology allows the simultaneous monitoring of expression levels of thousands of genes and even whole genomes. But the experiments themselves represent only the opening act. The grand ...

The study results challenge the current paradigm of microarray data analysis and suggest that the new method may improve identification of cancer-associated genes.

Unsupervised hierarchical clustering (UHC) analysis is a common method to profile the molecular expression of tissue microarray data. Methods: TM4: a free, open-source system for microarray data ...

A multidisciplinary team of pharmaceutics and computer-science researchers at the University at Buffalo, one of very few teams in the nation applying DNA microarray technology in studies of multiple ...

Patients and Methods Microarray analysis was performed on 14 normal oral epithelium and 71 HNSCCs from patients with outcome data. Spectral clustering (SC) analysis of the data set identified multiple ...

Last year, researchers led by Paul Coleman at the University of Rochester, New York, reported a microarray analysis of five AD brains which indicated that genes involved in trafficking synaptic ...