The prevalence and physiological importance of alternative splicing in multicellular eukaryotes has led to increased interest in its control. Much has been learnt about how transcription and ...

In this interview, we spoke to Adrian Krainer, a Professor at Cold Spring Harbor Laboratory, about his latest research into the role of RNA splicing in one of the deadliest forms of pancreatic cancer.

In any difficult transition, the elements that contribute revenue generally top the list of priorities. This is true for TV advertising as it moves along the inevitable digital transition path.

Alternative splicing, a clever way a cell generates many different variations of messenger RNAs - single-stranded RNAs involved in protein synthesis - and proteins from the same stretch of DNA ...

Mutations that disrupt the splicing code, or the machinery required for splicing and its regulation, have roles in a range of diseases. It is also becoming apparent that genetic variation that ...

Alternative splicing of DNA plays an important role in molecular biology – but how does it contribute to neurodegenerative disease? A new review from the University of California Riverside shows how.

While major splicing carries out 99.5% of this work, minor splicing is an indispensable process for the remaining 0.05% of genes, affecting about 700 of the 20,000 genes in the human genome.

In T cells, antigen-like stimulation increases expression of a splicing factor, driving splicing events that resemble those occurring during T-cell development.

Scientists have created a model to study the role of RNA splicing defects in Alzheimer's disease, revealing degeneration and toxicity caused by neuron hyperexcitability.

In this study, Shulman and his colleagues investigated a molecular mechanism called RNA splicing that is involved in the production of mature RNA molecules necessary to produce working proteins. They ...

Australian researchers have discovered a promising new strategy to suppress the growth of aggressive and hard-to-treat cancers by targeting a specialized molecular process known as "minor splicing." ...