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Abstract Self-assembling protein microarrays arrays can be used to study protein-protein interactions, protein-drug interactions, search for enzyme substrates, and as tools to search for disease ...
Protein and peptide microarrays, the emerging tools for proteomics and clinical assays, are high-throughput methods that track binding events and activities, and decide the function of proteins on ...
These three must be tightly merged with each other in order to provide accurate and best protein detection. The following are some of the label-free protein microarray detection methods.
This review outlines protein microarray techniques that are currently being used for analytical and function-based proteomics, providing a detailed analysis of recent advances in this technology.
A designed polypeptide scaffold contains a surface immobilization domain and a target capture domain for flexible protein arraying. 'Microarray' might just be the hottest buzzword in biology today ...
*These authors contributed equally to the preparation of this manuscript. Cell-based technologies for printing protein microarrays are faced with poor protein expression, protein insolubility ...
Potentially fragile microarray substrates are often used in protein microarray applications as they are suitable for maintaining protein structures required for capture/detection.
In addition to screening for protein–protein interactions, the microarray method can also be used to identify substrates for enzymes such as protein kinases, or to screen small molecule ...
Protein microarrays are one aspect of highly automated, large-scale biological screening technologies, the other is nucleic acid arrays.
A protein microarray is a piece of glass on which different molecules of protein have been affixed at separate locations in an ordered manner thus forming a microscopic array. These are used to ...
As genomics morphs into proteomics and the quest to understand the biological functions of proteins accelerates, researchers continue to look for the best methods that will speed their understanding; ...
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