A crucial step in DNA repair that could lead to targeted gene therapy for hereditary diseases such as 'children of the moon' and a common form of colon cancer has been found by scientists. Such ...

Divergent base excision steps converge to common steps for end processing, followed by repair DNA synthesis (represented as blue dots) and strand sealing. Polβ could also be involved in LP-BER by ...

UNSW researchers have identified a critical step in the molecular process that allows cells to repair damaged DNA – and it could mean big things for the future of anti-ageing drugs, childhood cancer ...

Researchers from Tokyo Metropolitan University have been studying DNA repair by homologous recombination, where the RecA protein repairs breaks in double-stranded DNA by incorporating a dangling ...

Chemistry DNA repair has been captured in a step-by-step molecular movie Researchers have worked out how a protein called photolyase repairs DNA using light, and their discoveries could guide the ...

(Nanowerk News) Researchers from Tokyo Metropolitan University have been studying DNA repair by homologous recombination, where the RecA protein repairs breaks in double-stranded DNA by incorporating ...

Genetic "mistakes" can occur following a certain form of error-prone DNA repair. Weizmann Institute scientists have now revealed how this two-step process takes place.

The second step involves the simultaneous arrival of the DNA excision repair proteins ERCC5 (XPG; 3'-endonuclease) and ERCC4 (XPF; 5'-endonuclease complexed with excision repair cross ...

In 1983, Sancar described the first step of a third DNA repair mechanism, called nucleotide excision repair, that fixes damage from ultraviolet light.

Tokyo, Japan – Researchers from Tokyo Metropolitan University have been studying DNA repair by homologous recombination, where the RecA protein repairs breaks in double-stranded DNA by ...